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A metabolic disorder occurs when abnormal chemical reactions in your body disrupt this process. When this happens, you might have too much of some substances or too little of other ones that you need to stay healthy. A lot of these metabolic disorders have been studied and the related genes have been identified. The human genome is around 3 billion bases, with around 1.4 million identified in 2001 (Lander et al., 2001). Since the publication of the human genome the cost has decreased and availability of genome sequencing and genetic testing has improved. Whole genome arrays, SNP chips, next generation sequencing and other technologies allow the general population to access information about their genome. With the increased access to this technology what are the ethical considerations?
Your task:
Write a 1000 word article suitable for a lay (non-science specialist) audience. Introduce one metabolic disorder related disease, outline what the Syndrome is, what treatment is if available, and what genes are related to the disease. Use this example to discuss one ethical issue around the increase availability of personal genome sequencing.

Be sure to include:
1) metabolic disorder
a. Reference
b. Description
c. Testing
d. Treatment
2) Ethics
a. Scope and implications clearly articulated
b. Provides balanced arguments both for and against viewpoint

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